Symphony® Thrombectomy System
Take the guesswork out of VTE.
Symphony is the only FDA-cleared, 24F and 16F pump-based thrombectomy system designed to take the guesswork out of venous thromboembolism (VTE) procedures by providing real-time feedback that enables physicians to make more purposeful, confident decisions.
VTE thrombectomy can lack predictability
The challenge in VTE procedures today is the lack of real-time information to guide physicians’ next steps, which can lead to repeated device introductions and exchanges and, most importantly, wasted time during an emergent procedure.
Real-time feedback with Symphony
- 16F/24F sizes to telescope and reach distal anatomy
- Directional control rotational collar
- On-demand pulses of vacuum
- Clot capture confirmation, in-line pressure monitoring & fluid injection
Anti-clogging ProHelix mechanical assist
Simplified procedure
Symphony’s multiport provides a direct line to the tip of the catheter, giving physicians immediate insight into clot and catheter position throughout the procedure. Confirm clot capture while distal in the anatomy, helping avoid the reintroduction of accessories that can add time and complexity to procedures.
One catheter from start-to-finish
Symphony is the only thrombectomy system that allows physicians to customize aspiration to match the patient’s needs. By adjusting the vacuum, physicians can maintain a 24F catheter throughout the entire case, targeting stubborn clot in challenging anatomies without limitations of small catheters.
Maintain position
The ProHelix Mechanical Assist device works over the wire and uses an Archimedes screw design to ingest corked clot without losing position or re-crossing the heart for faster, more efficient cases.
Symphony-PE Trial
Objective
To evaluate the safety and efficacy of the Symphony Thrombectomy System in the treatment of patients with acute intermediate-risk pulmonary embolism.
Safely and confidently focus on the patient.
0.9%
Major adverse event (MAE) through 48 hours
0.0% device-related serious adverse events (SAE)
0%
All-cause mortality rate
Measured through 30 days
250mL
Median aspirated blood
Minimal aspirated blood and no periprocedural blood transfusions
Large-bore power with precise deep vacuum significantly reduces clot burden.
38.4%
Clot burden reduction based on Refined Modified Miller Index
Largest reduction compared to IDE trials*
7mmHG
All-cause mortality rate
Measured through 30 days
0.44RV/LV
Median aspirated blood
Minimal aspirated blood and no periprocedural blood transfusions
Improved versatility, speed and control.
31min
Median device-use time
Fastest reported median time*
16F/24F
continuous deep vacuum
Rapid clot evacuation without increased blood loss
Streamlined
Procedure
Intraprocedural pulmonary artery pressure (PAP) assessment and contrast imaging
*A Prospective Multicenter IDE Study of the Next-Generation Precision Aspiration Thrombectomy System for Intermediate-Risk Pulmonary Embolism: The SYMPHONY-PE Trial
*No head-to-head clinical trials have been conducted.
Real-world Symphony cases
